Insight into Pharmacological Actions of Azadirachta indica (Neem) Leaf Extract

Abstract

Azadirachta indica, sometimes recognized as Neem, has been utilized for centuries for ritual and medical uses. This plant's accessibility and affordability have made it a popular choice for many individuals. Several studies have investigated the therapeutic potential of this plant, from its leaves to its bark. Neen is utilized in many traditional treatments because of its abundance of biologically active components. Nimbin, cyclic trisulfide, azadirachtin, nimbolide, nimbidin, mamoodin, and gedunin, among others, are used as spermicidal, antipyretic, hypoglycemic, antibacterial, immunomodulatory, antigastric ulcer, anti-inflammatory, antiarthritic, antifungal, diuretic, antimalarial and antitumor agents. Conventionally, diverse parts of the plant have been used by residents from various nations to treat a variety of diseases, including leprosy, eye problems, anorexia, skin ulcers, biliousness, intestinal worm elimination, epistaxis, and skin diseases such as burning consciousness, ringworms, wounds and itching. It additionally serves as a pain reliever, substitute treatment, and cure for fever and urinary problems. This study evaluated the anti-inflammatory and antioxidant properties of Azadirachta indica.